DNA reminder


www.glenarchive.com for more information

 To support the Glen DNA Archive at the Animal Health Trust … and support Glen health … please request a swab kit for your Glen. 

 Please do not forget to notify the AHT of any changes in your Glen’s health status … and also date & cause of death (including simply old age) when that sad time comes.

 If you already have swab kits but haven’t yet got around to swabbing your Glen, please dig out the kit & “do the deed” and get the swabs & documentation sent to the Animal Health Trust as soon as possible, please.




All change for gPRA testing.

It is no longer possible to have the DNA test for CRD3 in Glen of Imaal Terriers at Bochum University. Biofocus (also in Germany) have taken it over.

The form for submission is on http://www.biofocus.de/media/files/downloads/125_submission-form-v3-20180301.pdf

Information on how to take a swab http://www.biofocus.de/media/files/downloads/130_buccal-swab-collection-biofocus.pdf and 1 ml EDTA-Blood is sufficient

The price, if a member of a Glen breed club is 40,00 Euro plus 19% VAT, Non-members will have to pay 45,00 Euro plus VAT.

First clinic of the year

Optigen are offering up to 30% discount off DNA tests at Val Tiller’s next Optigen 20/20 Clinic on Tuesday 24th February 2015.

Glen of Imaal Terriers are invited to be DNA tested for crd3. Clients Attending: Blood sample collection for OptiGen tests from 1:30 pm.  Microchipping also available. Postal Participants: Full instructions provided for those who cannot attend.

Please contact Val Tiller for instructions regarding attendance at the clinic, or postal participation. Location: Foxbarton 15 Beaconsfield Road, Langley Vale, Epsom, Surrey  KT18 6HA

Email: val.tiller@talk21.com Phone: 01372 273597

Very interesting!

When Bochem and Optigen were looking for the rogue gene that caused PRA in Glen of Imaal Terriers, and finding again and again it wasn’t what they hoped, some people mused on a possible modifier. This was due to the diagnosed PRA affected dogs that, in some cases, just didn’t “Pee” i.e. didn’t Progress as per the name. Other folk were very sceptical about that idea and it has now been proven (thankfully) they were right and modifiers weren’t involved. This link is for those who said but it is very, very rare for such things to crop up-as you can see the ones that were wondering weren’t totally tilting at windmills.

Let’s start the week…..

….with something aimed for opinions!

The EFG is still waiting for word from the Kennel Club regarding official recognition but we aren’t just sitting doing nothing. One of the things up for consideration is updating the Code of Ethics. It’s a decent code but nothing really startling and the current climate requires more so how far should we go? As it says we shall already be asking about DNA testing to be included-one of the things up for debate-but what else? Some countries check for anything and everything, the Finns put it all online, but others do nothing at all on an official basis.

It has always been a proud boast that the EFG is for the Glen of Imaal Terrier in its entirety so thoughts are invited? It would be nice if opinions (keep it clean please) could be placed on here but even if you are shy about publicly expressing do send Jean your thoughts-they will be taken.

Where were we?

Pre Christmas it was asked what direction the blog should take? Political, more controversial, go deeper into things were three of the thoughts. Before the winter break eye testing came up….Ali Seall puts the following up for discussion.

The majority of Glen breeders are having their Glens DNA tested for GPRA-crd3, or they are using Hereditary Clear breeding stock.  BUT WHAT ABOUT EYE TESTING?  The Kennel Club Assured Breeder Scheme’s  Recommendation for member breeders is Annual Eye Testing.  GOITA’s Code of Ethics states, “It is recommended that all dogs should still be eye-tested periodically as a safeguard against further eye conditions.”  Professor Peter Bedford, Veterinary Ophthalmologist, writes for GOITA’s Health page, “As a breed you have already developed the discipline of eye examination and you should continue, to be certain that another problem does not become entrenched within the breed …… Eye examination is essential to ensure that our delightful breed remains free from other potential ocular [eye] disease.”

There has never really been any serious uptake of regular eye testing, other than from some breeders and some “show” people.  Looking at the figures now, it would appear that even “established” breeders have all but given up on eye testing their breeding stock.

ABS BREEDERS: Five of the six ABS breeders/breeding partnerships have produced 6 litters from bitches in their ownership in 2011 and 2012 i.e. since the DNA test for crd3 was introduced, but only one of the six bitches had an up-to-date eye certificate when she whelped i.e. within the 12 months prior to whelping.  Only one stud dog used over this time is owned by an ABS breeder; he sired 4 litters and his eye test certificate was up-to-date for just the first 2 litters.

BITCHES: Seventeen bitches have produced 18 litters during this time, and only three had up-to-date eye certificates.  These three bitches are all owned by first-time Glen breeders.  Seven bitches have never been eye tested.

DOGS: Nine dogs sired the 18 litters – one dog (x 4 litters); one dog (x 3 litters); two dogs (x 2 litters); and five dogs (x 1 litter).  Two stud dogs are resident in Ireland and so the testing status is unknown.  Two stud dogs have never been eye tested.  Four stud dogs had out-of-date eye test certificates.  The remaining stud dog is mentioned under ABS BREEDERS.

A number of Glens were eye tested and DNA tested at a Glen event in July 2010 – these dogs are not included in the following figures. The number of eye test results published in the Qtr 4 (Winter) 2010 to the Qtr 3 (Autumn) 2012 BRS (incl.) is for just 10 Glens.  There were 3 dog results, one of whom tested Affected, and 7 bitch results, one of whom was tested under the ECVO Scheme.  None of the 3 dogs have sired a litter over this time.  Three of the 7 bitches have whelped a litter during this time; they are the 3 bitches owned by first time breeders, and their certificates were “in date” at the time of whelping.

Both GOITA and Professor Bedford have recommended that we, as a breed, continue to eye test to screen for other eye problems.  I wonder if the poor uptake of eye testing is because people think that the Glen can’t possibly have any other form of eye disease …?  Unfortunately, there IS documented evidence that some Glens have developed other forms of hereditary and congenital eye disease.  The numbers are small, but there are conditions that are known to be hereditary, which suggests that there will probably be more cases.

Perhaps now is the time to review our eye testing recommendations?  It is breeders who proposed that eye testing should be done “periodically”.  But what does this mean …?  Should we not define the recommended frequency of eye testing for both breeders and “everyone else”?  It is disappointing to note that not one “established” breeder has had an eye test result recorded in the BRS since the DNA Screening Scheme for crd3 was established in October 2010 … and some breeding stock has never been eye tested.  The EFG still organises an annual event with eye testing by Professor Bedford, although it is noticeable that the numbers of Glens being tested has tailed right off.  GOITA has not organised eye testing since December 2009.

Perhaps we should just abandon eye testing?  Should we agree to remove the statements recommending periodic /regular eye testing from the breed club websites, and ask the KC to take off the ABS Recommendation for breeder members to do Annual Eye Testing?  Breeders, and especially those in positions of influence i.e. breed club officers and committee members should surely “lead by example” …?  If we are not eye testing our breeding stock, then why should we expect anyone else to bother …?

If we DO feel that we should continue eye testing our Glens, then perhaps we need to be a little more specific with our guidelines for breeders and for the rest of the Glen-owning community?  The breed club suggestions for eye tests to be done “periodically” and “regularly” are somewhat vague!   Any guidelines agreed should be realistic and achievable, and it is hoped that breeders would lead by example and follow any guidelines.

As a starting point for discussion, what about a recommendation for ALL Glens (including breeding stock) to be tested after the age of 10 years old, which would ensure that any potential late onset disease is also picked up?  For breeders, would it be reasonable to also recommend that any stud dog or brood bitch has an up-to-date eye certificate at the time of mating?  Hopefully, the EFG will continue annual eye testing and GOITA will reinstate annual eye testing – and breeders and breed club members will support these sessions.

A busy couple of weeks.

Normally the period after Christmas and early January is rather short of news but this year it’s been busy so the slightly new direction taken has obviously met with approval. Nevertheless though it’s time for the Winter Break and to gird loins for a (hopefully) equally as busy Spring and onwards. Let’s make it a date for February 18th to hit the EFG blog icon on your favourites list once again.

Before we all airkiss goodbye for a few weeks there are just a couple of things: Crufts online entries close on January 14th and this timely reminder, particularly after the post of two days ago.

If your Glen of Imaal Terrier has been DNA tested for GPRA-crd3, please can you check that the result is listed on the Kennel Club website: There are links to lists of all the Clear, Carrier and Affected Glens.

If your Glen’s results do not appear on the list, please send a COPY of the DNA result certificate (from Optigen or Bochum, both now send results direct to the KC but it could have been missed) to the Kennel Club to:

Health & Breeder Services Department, The Kennel Club, Clarges Street, Piccadilly, London, W1J 8AB

If you also want your Glen’s registration document updated, please send the original registration document (along with the copy of the test result certificate) and you will be issued with a new one, with the DNA status included.

Another couple of 2013 diary dates

Val Tiller (Foxbarton Border Collies) holds two (all breeds) Optigen (USA) DNA testing sessions a year – in February and September.

From Val:

“Optigen are offering 30% discount off DNA tests, paid for online, at Val Tiller’s next Optigen 20/20 Clinic, on TUESDAY 5th FEBRUARY 2013, in Epsom, Surrey.

Glen of Imaal Terriers are invited to be DNA tested for crd3-PRA. Clients may attend the clinic in person, or be Postal Participants. Contact Val Tiller direct for further details and to book places … ASAP … AS SHE IS AWAY FROM 8th-15th JANUARY.

E-mail: val.tiller@talk21.com or Tel: (01372) 273597.”

How’s the memory?

Four years ago (December 2008) the Kennel Club designated the month Breed Health Plan month and there was a lot of Glen of Imaal Terrier health discussion on, and off, the blog. Can you remember what was decided though? Have you thought about it since? Have you done anything else? We’re all very good-remarkably so compared to some breeds-with the PRA testing issue but what now or next?

Optigen Summer Special on PRA Testing

August 18, 2012 through September 04, 2012 – SUMMER DISCOUNT DAYS (OPEN
OptiGen will be offering our Summer Discount Days for online entries
starting August 18th through September 3rd. Entries need to be made
during that time using the code SPLASH812 for the maximum discount of
25%. Clients will have up to 30 days from the date of their online
request to get samples to OptiGen for testing. For more information,
please contact Becky at 607-257-0301 or email genetest@optigen.com.
Happy Summer!

Contact: Becky Iddings
Email: genetest@optigen.com